Skip to content Thyroid Disorders Grave’s Disease (hyperthyroid with goiter) Myxedema Hypothyroidism Hashimoto’s Disease (Autoimmune Thyroiditis) – Pathway/Axis: Hypothalamus/ Pituitary/Thyroid (HPT) Axis – Major cause: genes, gender/sex hormones, pregnancy, too much iodine, some drugs and radiation exposure – Major symptoms: Fatigue, weight gain, pale, puffy face, feeling cold, muscle pain, constipation, dry and thinning hair, heavy menstrual flow or irregular periods, depression, slowed heart rate, problems getting pregnant. Management: Primary Hypothyroidism Secondary Hypothyroidism Thyroid Storm (Thyrotoxicosis Crisis) Thyroiditis de Quervain’s Thyroiditis – Pathway/Axis: hypothalamic/Pituitary/Thyroid (HPT) axis – Major cause: viruses such as mumps, influenza, and other respiratory viruses infect the thyroid gland and cause inflammation which damages the follicular cells of the thyroid. – Major symptoms: Neck pain, fever, fatigue. Damage to the thyroid follicular cells can cause hyperthyroidism which leads to weight loss and anxiety. Infectious (Suppurative) Thyroiditis Painful Subacute Thyroiditis Painless Lymphocytic Thyroiditis Riedel Thyroiditis Silent Thyroiditis – Pathway/Axis: Hypothalamic/Pituitary/Thyroid (HPT) Axis: – Major cause: unknown, but related to immune attack against the thyroid, leading to the hyperthyroid phase. Once stores on thyroid hormones are depleted the hypothyroid phase beings. Usually occurs in postpartum women, but can be caused by medicines such as interferon and amiodarone. – Major symptoms: “silent” refers to the absence of thyroid tenderness that occurs in subacute thyroiditis. thyroid enlargement with a self-limited hyperthyroid phase several weeks, followed by a hypothyroid phase during which many women are diagnosed. Eventually, recovery to the euthyroid state occurs but the hypothyroid can occasionally become permanent. Eye signs and pretibial myxedema do not occur Thyroid Mass Goiter Non-Palpable (Incidental) Thyroid Nodule Solitary thyroid nodule Anaplastic Thyroid Carcinoma Follicular carcinoma Medullary Thyroid Carcinoma Papillary Carcinoma Toxic Thyroid Adenoma Scroll Up error: Content is protected !!