Pituitary Disorders

Pituitary Disorders


  • – Pathway/Axis:
    • Growth hormone
  • – Major cause:
    • tumor of the anterior pituitary gland called a pituitary adenoma.
    • Causes anterior pituitary to produce excess growth hormone after the closure of the epiphyseal plate during puberty.
  • – Major symptoms:
    • hands, feet, nose, lips, and ears show swelling of the soft tissue, and skin starts to thicken.
    • Swelling if internal organs, deep voice due to swelling of vocal cords, jaw or brow protrusion, and expansion of the skull at the fontanelle.
    • Enlargement of the tongue. Severe headaches, arthritis, hypertension, diabetes mellitus. Possible heart and kidney failure.

Empty Sella Syndrome


Lymphocytic hypophysitis

Pituitary dwarfism

Sheehan syndrome

Pituitary Cancers

Pituitary adenoma (Prolactinoma)

Pituitary apoplexy

Pituitary during pregnancy

  • – Increased estrogen -> hyperplasia of prolactin-secreting cells -> increased prolactin -> INCREASED PITUITARY SIZE
  • – Vascular supply remains the same despite the increased pituitary size 

Show Buttons
Hide Buttons
error: Content is protected !!