Parathyroid Disorders

Parathyroid Disorders

Primary Hyperparathyroidism

  • – Pathway/Axis:
    • parathyroid hormone
  • – Major cause:
    • parathyroid adenoma – when one or more of the parathyroid glands grows into a tumor and secretes excess parathyroid hormone resulting in high blood calcium levels.
  • Risk:
    • – osteoporosis, kidney stones, excessive urination, abdominal pain, tiring easily or weakness, depression or forgetfulness, and bone and joint pain.
  • Management:

Secondary Hyperparathyroidism

Tertiary Hyperparathyroidism


Parathyroid adenoma


  • Pathway/Axis:
    • Calcitonin- Parathyroid hormone (PTH) feedback loop
  • – Major cause:
    • many different causes; typically due to a decrease in calcitonin secretion or an increase in PTH secretion.
  • – Major symptoms:
    • greatly increases risk in bone fractures. fractures occur in situations where healthy individuals wouldn’t normally break a bone, like the vertebral column, rib, hip, and wrist.

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