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- Pretibial myxedema is a complication of Graves disease, whether it presents as hypo-or hyperthyroidism.
- It is a dermopathy that most often occurs in the lower legs and results from increased deposition of mucin due to the endocrine abnormality.
- Diabetes mellitus can cause necrobiosis lipoidica, a lesion on the lower extremities;
- hyperlipidemia can cause waxy papules; and collagen vascular and ischemic disease can cause urticaria and/or ulceration.
Indications for surgery in a patient with hyperparathyroidism
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