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Typical treatment of mild to moderate acne vulgaris
- Topical retinoids such as adapalene and benzoyl peroxide are first-line therapy and a trial of therapy is typically 8-12 weeks.
- Topical antibiotics may be added to topical retinoids or benzoyl peroxide to achieve better symptom control. To decrease emerging antibiotic resistance, studies support limiting antibiotic use to 12 weeks except in severe cases, not using antibiotics as monotherapy, and using clindamycin rather than erythromycin.